CBD, also known as CBD, is a chemical substance found within the plant Cannabis Sativa. When applied topically or consumed by inhalation of smoke or through edible consumption, CBD can interact with neuroreceptors of your endocannabinoid gland, which transmits signals between cells to manage your mood, movement, and homeostasis, as well as your immune system.
CBD is usually taken from Cannabis Sativa plant oil form and then mixed with an inert oil carrier, such as hemp seed oil, to consume. Of the 60 percent of U.S. Five percent are using CBD oil and tinctures for specific in an upcoming Forbes Health survey of 2,000 U.S. adults conducted by OnePoll.
CBD research is on the rise and growing. There are nine different ways that studies suggest CBD oil can improve your well-being.
1. Offset anxiety and Depression.
CBD’s ability to calm is its most well-known feature and the reason that CBD’s use is so widely used. A study from 2017 published in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 people who were simulated to speak in a test. Some were given a placebo; others were treated with 150 milligrams, 300 milligrams, 300 milligrams, or 600 milligrams of CBD before their speech. The participants who received the 300 milligrams of CBD had significantly fewer anxieties during the tests than those who were given a placebo. Incredibly, those who received 150 or 600 milligrams of CBD were more anxious during the test than those who received 300 milligrams.
At the very least, one research study on mice showed CBD has effects similar to imipramine, an antidepressant. Human trials are required to confirm the possibility that CBD could trigger the same antidepressant response in our bodies.
2. Treat Select Epilepsy Syndromes
In certain instances, CBD is sometimes used to treat epileptic seizures.
In the year 2018, The Food and Drug Administration (FDA) approved the use of CBD under the brand name Epidiolex to treat seizures that result from Lennox Gastaut syndrome as well as Dravet syndrome, two rare forms of epilepsy that are only available to patients who are at least two years old.
Three studies that have been thoroughly vetted provide the evidence needed to support this FDA’s choice. In these studies, 516 patients suffering from Lennox Gastaut syndrome and Dravet syndrome were treated with either Epidiolex or an alternative. Epidiolex is a medication that, when used with other medicines prescribed, has reduced the frequency of seizures compared to a placebo.
3. Reduce PTSD Symptoms
In a study of limited size in 2018 published in the Journal of Alternative and Complementary Medicine, eleven patients with Post-traumatic Stress Disorder (PTSD) took CBD in addition to regular psychotherapy for 8 weeks in an outpatient psychiatric facility. Ten of them experienced an improvement in the severity of their PTSD symptoms. CBD was generally well-tolerated, according to the research.
Margaret Rajnic, a doctor of nursing practice with experience in CBD and medical cannabis, stresses the necessity of using therapy in conjunction with any CBD or cannabis for PTSD. “There is an amount of therapy needed for PTSD,” she states. “But CBD will give you that little bit of decreased anxiety.”
Four other human trials from 2012 to 2016 suggest CBD reduces PTSD symptoms, although some include THC, or tetrahydrocannabinol, the main mind-altering element in cannabis. If THC and CBD combine and interact, they produce what’s known as”an “entourage effect,” complementing the benefits of each. For instance that taking the same amount of THC and CBD can reduce THC’s “high” from THC and just a bit THC combined with CBD can enhance CBD’s effects.
4. Treat Opioid Addiction
A few studies, both in preclinical animal studies and clinical trials on humans, suggest CBD may be used in the future for those who are dependent on opioids.
In one study, researchers conducted a study in which they administered CBD to patients suffering from heroin addiction disorders. During one week, CBD drastically reduced users’ cravings for cues and withdrawal anxiety, as well as resting heart rate and blood levels of cortisol in saliva. There were no serious adverse reactions discovered.
Other studies show CBD is useful in reducing different medical and psychological symptoms such as insomnia, anxiety, and pain for patients suffering from addiction disorders. This suggests that CBD could be a viable treatment for opioid dependence. However, further research is required.
5. Alleviate ALS Symptoms
Amyotrophic lateral sclerosis (ALS) causes nerve cells within the spinal cord and brain to weaken, leading to losing muscle control that becomes more severe with time. It’s unclear why ALS occurs, though it is possible to inherit the condition in certain instances. No cure’s been discovered, and two FDA-approved medicines are available to manage ALS symptoms.
Studies suggest that those with ALS might benefit from the effects of the entourage created through the combination of CBD and THC, similar to those with PTSD. In a study in 2019, participants received a mix of THC and CBD with different dosages based on their requirements and preferences. Patients who suffer from mild, moderate, or extreme spasticity (muscle stiffness and tightness) because of ALS were greatly satisfied with the treatment. Patients with severe or moderate spasticity had higher satisfaction ratings than those with mild spasticity.
6. Relieve Unmanageable Pain
The year 2005 was the first time Canada authorized the usage of Sativex, an oromucosal (absorbed within the mouth’s lining) spray containing equal amounts of THC and CBD for treating central nerve pain. In 2007 Canada allowed the use of the medication again to treat cancer-related pain that was not responding to other drugs.
While ongoing research within research in the U.S. indicate, CBD is effective in treating non-cancer, chronic pain. In one study from 2020, the researchers applied CBD daily to a set of patients suffering from symptoms of peripheral neuropathy (a result of damage to the brain and spinal cord nerve injury), and another group of patients with similar conditions received a placebo. Results showed a significant decrease in sharp, intense discomforts and itchy, cold sensations for those who took the topically applied CBD compared to those who took the placebo. There were no reports of adverse negative side effects.
When applied through a topical application, CBD oil doesn’t affect the systemic problem like it would if it was directly in the bloodstream. However, topically CBD oil is more targeted and targets the pain in a specific location. Because it’s more immediate and clear, it could have a greater impact.
7. Ease Diabetic Complications
To begin, tests on human cells showed that CBD can help reduce the impact of elevated glucose levels on other cells of the body. This usually is the precursor to the progression of diabetes and other complications. Researchers concluded that, with further research, CBD could have significant advantages when applied to people with diabetes or diabetic complications, as well as plaque buildup within the walls of arteries.
In a smaller study, 13 people who had type 2 diabetes that wasn’t taking insulin were treated with both CBD and placebo (in place of the insulin). Researchers found that CBD reduced their levels of the hormone called resistin (which results in resistance to insulin which is the hormone that controls the levels of sugar) and also increased the amount of the glucose-dependent insulinotropic peptide (a hormone that helps ensure the release of insulin in digested foods) in comparison to their baseline levels before the start of the study. The results suggest CBD may be a natural diabetes treatment, as it helps the body control the levels of hormones related to insulin.
8. Protect Against Neurological Disease
Studies in the preclinical and clinical stages show that CBD has anti-inflammatory and antioxidant properties. These properties are believed to be a significant source of neuroprotection or protection against various pathological diseases.
Numerous preclinical studies indicate that CBD may positively act against Parkinson’s disease, Multiple sclerosis, and Alzheimer’s disease. Brain ischemia and Huntington’s disease also were studied. However, significant positive results weren’t recorded. More clinical studies are required to prove CBD’s effectiveness when used as a treatment for these diseases.
9. Inhibit Arthritis Symptoms
Arthritis causes the degeneration of the tissues in and around joints. There are many kinds of arthritis. The symptoms include stiffness, pain, and loss of mobility. The treatment for arthritis usually focuses on pain relief and improved joint function.
A study in 2006 revealed that Sativex, a botanical drug derived from CBD approved within the United Kingdom in 2010–promoted statistically significant improvements in the quality of rest, pain moving, and at rest in people who have Rheumatoid arthritis when compared to placebo. The study was the initial controlled study of Sativex as a treatment option for Rheumatoid arthritis that involved more than 58 patients. CBD was shown to possess an anti-pain effect and the capacity to reduce disease activity.
In 2023, in an investigation of more targeted treatment, researchers applied synthetic CBD gel in 250-milligram or 500-milligram doses daily or as a placebo to knee pain caused by osteoarthritis. Patients were also advised to stop taking painkillers or anti-inflammatory drugs other than Acetaminophen before and during the study.
The results were fascinating but needed to be more conclusive. One thing is certain: people treated with CBD didn’t experience any changes in pain compared to placebo-treated patients. However, there were statistically significant differences between those who received the 250-milligram dose and the control group measuring the average improvement in weekly of their most painful levels as well as the WOMAC (Western Ontario and McMaster Universities Arthritis Score) physical function score. In addition, males appeared to gain more from CBD than women in this study.